pypath.inputs.uniprot.uniprot_data

pypath.inputs.uniprot.uniprot_data(*query, fields: str | Iterable[str] | None = None, organism: str | int | None = 9606, reviewed: bool | None = True, **kwargs) → dict[str, str] | dict[str, dict[str, str]]

Basic client for the UniProt REST API.

Retrieves one or more fields from UniProt, by default for all reviewed (SwissProt) proteins of one organism

Parameters:

• query – Query elements: can be a ready query or its components, bypassing the processing in this function or performing only simple concatenation. Alternatively, it can be a nested structure of lists and dicts describing more complex queries. See the examples below.

• fields – One or more UniProt field name. See details.

• organism – Organism name or identifier, e.g. “human”, or “Homo sapiens”, or 9606.

• reviewed – Restrict the query to SwissProt (True), to TrEMBL (False), or cover both (None).

• kwargs – Same as passing a dict to query.

Details:

The query can be built in several ways: - Simple string or concatenation of strings:

query_builder(‘kinase AND organism_id:9606’) query_builder(‘kinase’, ‘organism_id:9606’) query_builder(‘kinase’, organism_id = 9606) The above 3 examples all return the same query: kinase AND organism_id:9606

• The default operator within lists is OR and within dicts is AND: query_builder(organism = [9606, 10090, 10116]) organism_id:9606 OR organism_id:10090 OR organism_id:10116 query_builder({‘organism_id’: 9606, ‘reviewed’: True}) organism_id:9606 AND reviewed:true

• These default operators can be changed by including the op key in dicts or including the operator with an underscore in lists: query_builder({‘length’: (500,), ‘mass’: (50000,), ‘op’: ‘OR’}) length:[500 TO *] OR mass:[50000 TO *] query_builder(lit_author = [‘Huang’, ‘Kovac’, ‘_AND’]) lit_author:Huang AND lit_author:Kovac

• The nested structures translate into nested parentheses in the query: query_builder({‘organism_id’: [9606, 10090], ‘reviewed’: True}) (organism_id:9606 OR organism_id:10090) AND reviewed:true

• Values are converted to strings, intervals can be provided as tuples: query_builder({‘length’: (100, None), ‘organism_id’: 9606}) length:[100 TO *] AND organism_id:9606

For a complete reference of the available parameters, see https://www.uniprot.org/help/query-fields and https://www.uniprot.org/help/text-search for additional syntax elements.

For the available fields refer to the _FIELD_SYNONYMS attribute of the UniprotQuery class or the UniProt website: https://www.uniprot.org/help/return_fields

Returns:

• A list of UniProt IDs if no fields were provided.

• A dict of UniProt IDs and corresponding field values if exactly one field was provided.

• A dict with field names as top level keys and dicts of the kind described in the previous point as values.