pypath.inputs.dorothea.get_dorothea_old

pypath.inputs.dorothea.get_dorothea_old(levels={'A', 'B'}, only_curated=False)

Retrieves TF-target interactions from DoRothEA.

Parameters:

• levels (set) – Confidence levels to be used.

• only_curated (bool) – Retrieve only literature curated interactions.

Details

DoRothEA is a comprehensive resource of TF-target interactions combining multiple lines of evidences: literature curated databases, ChIP-Seq data, PWM based prediction using HOCOMOCO and JASPAR matrices and prediction from GTEx expression data by ARACNe.

For details see saezlab/DoRothEA.